KOC is an abbreviation that can mean:

• Kings of Convenience, a Norwegian indie musical group
• Knights of Columbus, a Roman Catholic fraternal order
• Kodiak College, a college located in Kodiak, Alaska
• Kuwait Oil Company, one of the biggest oil companies in the world
• Korean Olympic Committee, represents South Korea in handling international affairs related to the Olympic Movement
• "Knights of Cydonia", a song by the British band Muse
• Kingdom of Comfort, a Delirious? album
• Kingdoms of Camelot, an online game by Kabam
• Kevin O'Connell, an American football coach and former player

In Chemistry:

• Koc (Soil Organic Carbon-Water Partitioning Coefficient), the ratio of the adsorbed organic analyte to the dissolved